Interleukin-11 Promotes the Progress of Gastric Carcinoma via Abnormally Expressed Versican

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Interleukin-11 Promotes the Progress of Gastric Carcinoma via Abnormally Expressed Versican

Versican, a ubiquitous component of the extracellular matrix (ECM), accumulates both in tumor stroma and cancer cells and is highly regulated by various cytokines. The aberrant expression of versican and its isoforms is known to modulate cell proliferation, differentiation, and migration, all of which are features of the invasion and metastasis of cancer; versican is also known to favour the ho...

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ژورنال

عنوان ژورنال: International Journal of Biological Sciences

سال: 2012

ISSN: 1449-2288

DOI: 10.7150/ijbs.3579